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Changing medicines, if they are causing the problem.Promoting a person's self-care and independenceĭepending on the cause, treatment may include:.Vitamin deficiency ( vitamins B12, B1, and E).Drug-related neuropathy, including chemotherapy.Long-term (chronic) inflammatory neuropathy.Cancer (called a paraneoplastic neuropathy).Autoimmune disorders, such as Sjögren syndrome.Possible causes of sensorimotor polyneuropathy include: Some diseases lead to polyneuropathy that is mainly sensory or mainly motor. Diseases that destroy the glue (connective tissue) that holds cells and tissues together.Autoimmune (when the body attacks itself) disorders.Some neuropathies develop over years, while others can start and get severe within hours to days. Damage to the nerve fiber or entire nerve cell can make the nerve stop working. Damage to the covering of the nerve cell causes nerve signals to slow or stop. Sensorimotor polyneuropathy is a bodywide (systemic) process that damages nerve cells, nerve fibers (axons), and nerve coverings ( myelin sheath). It can also affect both, in which case it is called a sensorimotor neuropathy. Neuropathy can affect nerves that provide feeling (sensory neuropathy) or cause movement (motor neuropathy). Polyneuropathy means that many nerves in different parts of the body are involved. Mononeuropathy means one nerve is involved.

When it occurs outside of the central nervous system (CNS), that is, the brain and spinal cord, it is called a peripheral neuropathy. Neuropathy means a disease of, or damage to nerves.
